Archive for November, 2008...
Filed under Uncategorized, health
Protein from sea cucumber that can be used as potential weapons to fight and stop the spread of malaria parasites. Therefore the study of the Research UK.
Studies done by the Campus Imperial College, London is published in Plos Ptahogens entitled “to use weapons of protein-III cells could prevent the mosquitoes through a parasite” that is a step toward the development of new ways to prevent the spread of malaria have been found.
When the mosquito suck blood in the human malaria infection, malaria parasites develop into the complex. This report says, the early indications that the protein from the sea cucumber can be very effective in more than four different parasites that can cause malaria.
Sea creature like a snail, or often referred to as the sea cucumber lectin protein that produces the growth of parasites can be unnerving.
An international team of researchers, the genetic set mosquitoes that carry malaria parasites to produce the same protein in their system perncernaan when the mosquito-eating mosquitoes. Plos Pathogen The study found that the sea cucumber protein could destroy even the growth of parasites in the mosquito’s stomach.
Malaria has been as much infect 500 million people per year worldwide, and has as much to kill 1 million people per year. Estimated that 40 percent of the world population is at risk of the spread of this death. In order to stimulate mosquitoes to produce lectin, the researchers incorporate genes from the sea cucumber which produces a protein with the genes of insects. The results show that this technique is very effective against some parasites that cause malaria.
Lectin is poisonous to some of these parasites, when they were still in the early stages of growth called the ookinete. Usually, the ookinete migrate through the mosquito stomach wall and produce thousands of identical cells that attacked the sweat gland, and human infection when mosquitoes suck human blood.
However, when exposed to lectin, ookinete directly killed before they start to turn off the action human infection. One of the researchers, Profesod Bob Sinden Campus of Imperial College, London states that the results of this study is very promising and show a reverse genetic for mosquitoes in this way, was clearly to give direct effect on the parasite’s ability to cleave cel even in the mosquito’s body itself.
However, he said, a lot of work to be done before this technique can be used to control malaria. “Although the sea cucumber protein significantly reduces the number of cells in the mosquito malaria parasite, but it does not work on a total of all insects.
At this stage of growth stages, a genetic modifying mosquitoes will be very dangerous for people. Specifically, our goal is how to find a way to reverse the mosquito, so that the malaria parasite does not develop “he explained.
Professor Krishna Sanjeey, malaria expert at the School Health St George Hospital, London, states that a new treatment for malaria is very important. For some new findings, that the malaria parasite now resistant to begin drug artemisinin that.
“This is very important and is the first step in the development of new potential ways to control malaria infection,” he said.
Ron Behrens from the London School of Hygiene and Tropical Medicine said that this technique shows a new theory. However, he reminded that the introduced mosquito, which is genetic already very difficult to practice. “You must get modified version to become a dominant species before, and it really has not been done before,” he said.
Previous research also indicate that, with the target protein can be a key to help the growth of malaria parasites that are resistant to the start of medicines which have at this time. Protein bring these parasites from red blood cells that are able to attack cells on the side. Inhibit the protein, the parasite attacks stop, and can assist in the development of new anti malaria drugs.
The team from the National Institute for Medical Research has been working with the protein, an enzyme which is called as PfSUB1 for a decade. But until now they did not know that it can affect the body in malaria Maintenance.
Plasmodium falciparum parasites that cause malaria to become self-propagate in the red blood cells so that the parasite known merozoites, are ready to infect other cells.
Filed under health
Cigarette smoke exposure or passive smokers in the five risk can encourage children affected by allergies. Swedish researchers so disclosed. A team of researchers at the Karolina Institute, Stockholm analyze a list of questions (questionaire) by parents who filled more than 4,000 families.
Parents fill in answers, when their baby aged two months, 12 months, 2 years and 4 years. Then the researchers collected blood samples from more than 2500 children at age 4 years to examine the percentage rate immunoglobin E (IgE), which appear by the body’s immune system to respond on the allergy. High IgE levels mengindikasi sensitive allergy.
8 percent as much a mother smoking during their pregnancy and 12 percent smoked during part of the pregnancy period. However, the researchers found no evidence that smoking during pregnancy can result in children at risk to become sensitive to certain allergies. However, 20 percent of maternal smoking after the baby they were born, and 4 percent of children exposed to cigarette smoke to be passive smokers from both their parents.
Of the overall, 25 percent of children had high IgE levels, at the time they are 4 years old, with 15 percent allergic to a respiratory allergy, 16 percent allergic to food, and 7 percent allergic to both these forms of allergy. Compared with children who are not exposed to cigarette smoke, children are exposed to cigarette smoke during a baby twice the risk respiratory allergies, such as when to meet pets. And 50 percent to the food allergy. Results of this study in the publication in a scientific journal Thorax.
Indeed, smokers due to passive exposure to cigarette smoke . Also known as environmental tobacco smoke from the (ETS), which can be identified from baunya. ETS mengontaminasi air and detained in the clothing, hangings and other household tools. Many people feel that the ETS is not very comfortable, and iritateeyes and nose. More important, it can be dangerous to health. More than 4,000 types of different chemical substances identified in the ETS, and 43 chemical substances in them can cause cancer. Almost 26 percent of adults in the United States (U.S.), smoking, and 50-67 percent of children living at home have at least one adult smoker that.
Although ETS is dangerous for all people, including a baby, fetus, children, the age group most affected by risk. This is because ETS can damage the growth of the cell body organs, such as the lungs and brain.
Passive smokers to give effect to the fetus and the birth of death among infants and the fetus, changes in blood flow placenta when a woman is being pregnant. Although the long-term health effects for pregnant women are exposed to cigarette smoke is still not known.
Some research studies show that smoking during pregnancy can cause harelip, or other. Mothers breastfeeding smokers production is reduced, and the baby they have lower body weight. Maternal smoking is also associated with infant death syndrome death of a baby suddenly, the main cause of death among infants aged one month to one year.
Cigarette smoke exposure can reduce the damage and lung function in children of all ages. Also increase the frequency of asthma of children. Passive smokers can aggravate sinusitis, rhintis, asthma and several types of children. In the children aged under two years of cigarette smoke exposure increase the risk of bronchitis and pneumonia. In fact, a study in 1992 done by the Environmental Protection Agency that ETS causes respiratory infections 150000-300000 in infants and children under the age of 18 months. This disease should result in 15,000 cases treated in the hospital. Child’s parents half a pack of cigarettes smoker per day or more doubled the risk must be treated in the hospital because of respiratory disease.
ETS exposure increase the number of ear infections will be experienced by children, and increasing the duration of this disease. Breathe cigarette smoke the Eustachian tube related to the back of the nose and middle ear. This causes swelling and pressure disturbances in the middle ear, causing pain, removing the fluid, and infection. Ear infections are the main functions of hearing loss in children. If it does not get immediate medical care, surgical operations and ear duct network will be the only way out.
While the effect on the brain of children, mothers of smokers during pregnancy are the children will have behavioral problems such as a hyperactive than children who are not his mother smoker. Being low in the school both in the intellectual activities and also has as one of the consequences. Passive smokers also cause cancer 100 times larger. ETS causes 3000 cases of lung cancer that they are not smokers each year. Finally, this is a warning alarm for all people, to immediately stop giving cigarette smoke on children and make them stop from becoming passive smokers from now on.