PROGRESS medical science have brought the hope for curing various diseases. However, there are some diseases that until now could not be corrected with treatment technique.
Hepatitis or liver disease and cirrhosis is a disease that attacks the liver organ. Medicine has given the latest hope for survival of the patient’s disease, but when it has been in the cirrhosis, the treatment of any kind have no meaning.
Hope now appears from the latest research on new treatments cirrhosis and liver disease dangerous to others. In fact, this treatment can affect the likelihood of dangerous diseases, such as scleroderma and pulmonary fribosis.
Exercise is an important organ in the human body. Occur in the liver processes important for human life, from the energy storage process, the formation of protein, acid and bile, the cholesterol metabolism, to neutralize poisons or medicines into the body.
Liver damage may be caused by several factors such as illness, injury or poison. If this condition continues to occur, it will be harmful to other networks called liver fibrosis.
If the fibrosis does not get the handling right, the more severe the damage and develop into cirrhosis. Cirrhosis is a condition when the heart is very much disturbed due to the network in the heart ligament.
Travel disease marked ligament in the heart of the network, network and grow to dangerous heart. Until now, there is no way to oppose or prevent the occurrence of this process.
“The situation will be worsened when a normal protein called RSK increasingly active in the liver cells,” said researchers from the University of San Diego Martina Buck PhD.
Based on research carried out, using a genetic mouse Buck producing RSK to block peptide-protein particles, so that does not develop into liver fibrosis and liver poison. Furthermore, the peptide injected into normal mice and protect the functioning of the liver toxin.
“All mice in the control group suffered fribosis heart, while mice receiving the peptide resistor RSK little or not at all experienced heart fibrosis,” Buck is also a researcher from the San Diego VA Healthcare System.
Heart cells called hepatic stellate cells (HSCs) should not produce a natural material called collagen is too many. Because the network is broken form of collagen. Excessive collagen production can be caused due to pressure injury or disease.
Resistor peptide RSK activity HSCs that caused “damage” themselves. The cells in normal liver cells will continue to heal the heart. “The result, HSCs are dead akan possible injury on the recovery network,” said Buck.
If the production of HSCs in humans too much, the same condition also occurs in mice. Thus, the invention can be used to overcome the disease in humans. Therefore, Buck and the team hopes the findings resistor peptide RSK become one of the alternative treatment in humans in the future.
“Researchers speculate this invention will facilitate the development of small molecule which has the potential to prevent and overcome liver fibrosis,” Buck said.
He added, resistor, and the development of liver fibrosis would decrease the stadium since the first liver cancer risk of cancer increases when the entry conditions in the liver cirrhosis. The problem is, people with cirrhosis do not realize the symptoms and complaints of this disease. In fact, patients often come in the situation worse.
Staff Department of Surgery Denver Health Medical Center Jeffrey A Gunter MD said, if the more severe complications, the patient should be immediately to the hospital to get the right treatment. “The heart is the fade does not work normally. This is dangerous,” he said.
